ZFPM1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120619-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5120619 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
ZFPM1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ZFPM1
Gene Alias
FOG; Fog1; FOG-1; friend of GATA 1; friend of GATA protein 1; Friend of GATA-1; ZC2HC11A; ZFN89A; Zfpm1; Zinc finger protein 89A; Zinc finger protein multitype 1; Zinc finger protein ZFPM1; zinc finger protein, FOG family member 1; zinc finger protein, multitype 1; ZNF408; ZNF89A
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
161882, 22761, 691504
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1.18 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
O35615, Q8IX07
Gene Symbols
ZFPM1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human ZFPM1 (NP_722520.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: HepG2, Mouse liver, Mouse brain, Rat liver
- Immunogen sequence: MSRRKQSNPR QIKRSLGDME AREEVQLVGA SHMEQKATAP EAPSPPSADV NSPPPLPPPT SPGGPKELEG QEPEPRPTEE EPGSPWSGPD ELEPVVQDGQ RRIRARLSLA TGLSWGPFHG SVQTRASSPR QAEPSPALTL LLVDEACWLR TLPQALTEAE ANTEIHRKDD ALWCRVTKPV PAGGLLSVLL TAEPHSTPGH PVKKEPAEPT CPAPAHDLQL LPQQAGMASI ZFPM1 is a transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation
- ZFPM1 is an essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3
- Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context
- The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1
- ZFPM1 may be involved in regulation of some genes in gonads
- ZFPM1 may also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2.