Urokinase Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120798-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5120798 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
Urokinase
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PLAU
Gene Alias
antagonist of uPA; ATF; BDPLT5; CD87; HGNC:9052; plasminogen activator; plasminogen activator, urinary; plasminogen activator, urokinase; Plau; QPD; uPA; u-PA; UPAM; UPAR; U-plasminogen activator; Urinary plasminogen activator, urokinase; URK; URKR; Urokinase-type plasminogen activator; Urokinase-type plasminogen activator chain B; Urokinase-type plasminogen activator long chain A; Urokinase-type plasminogen activator short chain A
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
18792, 25619, 5328
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
1.573 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P00749, P06869, P29598
Gene Symbols
PLAU
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 20-180 of human PLAU (NP_002649.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: HT-1080, Mouse kidney, Mouse brain, Rat kidney, Rat brain
- The target is usually found in the following locations: Secreted
- Immunogen sequence: GSNELHQVPS NCDCLNGGTC VSNKYFSNIH WCNCPKKFGG QHCEIDKSKT CYEGNGHFYR GKASTDTMGR PCLPWNSATV LQQTYHAHRS DALQLGLGKH NYCRNPDNRR RPWCYVQVGL KPLVQECMVH DCADGKKPSS PPEELKFQCG QKTLRPRFKI I This gene encodes a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation
- A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding
- This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen
- Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain
- This two-chain derivative is also called HMW-uPA (high molecular weight uPA)
- HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment
- LMW-uPA is proteolytically active but does not bind to the uPA receptor
- Alternatively spliced transcript variants encoding different isoforms have been found for this gene.