USP8 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA527947-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA527947 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
USP8
Classification
Polyclonal
Conjugate
Unconjugated
Gene
USP8
Gene Alias
AI574262; AW557536; Deubiquitinating enzyme 8; hUBPy; HumORF8; Kiaa0055; mKIAA0055; mUBPy; putative deubiquitinating enzyme; SPG59; Ubiquitin carboxyl-terminal hydrolase 8; ubiquitin isopeptidase Y; ubiquitin specific peptidase 8; ubiquitin specific protease 8; ubiquitin thioesterase 8; ubiquitin thiolesterase 8; ubiquitin-specific-processing protease 8; Ubpy; USP8
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
84092, 9101
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.
P40818, Q80U87
Gene Symbols
USP8
Immunogen
Recombinant fragment corresponding to a region within amino acids 203 and 528 of Human USP8
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Recommended positive controls: H1299, HCT116
- Predicted reactivity: Rhesus Monkey (95%), Bovine (83%)
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- USP8 is a ubiquitin specific protease that plays an important regulatory role at the level of protein turnover by preventing degradation
- USP8 is involved in cell proliferation, and probably regulates the stability of STAM2 and RASGRF1
- USP8 may regulate T-cell energy mediated by RNF128 via the formation of a complex containing RNF128 and STAM2
- As revealed by structure/function studies, USP8 forms a ternary complex with RNF128 and OTUB1, and interacts with the SH3 domain of STAM2 and RASGRF1
- Expression of USP8 is induced Upon growth stimulation in starved human fibroblasts, and expression decreases in response to growth arrest induced by cell-cell contact.