ITGB5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5120815-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5120815 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
ITGB5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Itgb5
Gene Alias
[b]5; [b]-5; [b]5A; [b]5B; AA475909; AI874634; beta5; beta-5; CD61; ESTM23; FLJ26658; GP3A; GPIIIa; I79_000655; integrin beta 5; integrin beta-5; integrin subunit beta 5; integrin, beta 5; ITGB5; RGD1563276; testis secretory sperm-binding protein Li 217p
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16419, 257645, 3693
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.42 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
O70309, P18084
Gene Symbols
Itgb5
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 490-720 of human ITGB5 (NP_002204.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: Mouse brain, Mouse kidney, Mouse liver, Rat brain, Rat liver
- The target is usually found in the following locations: Membrane, Single-pass type I membrane protein
- Immunogen sequence: SPGYLGTRCE CQDGENQSVY QNLCREAEGK PLCSGRGDCS CNQCSCFESE FGKIYGPFCE CDNFSCARNK GVLCSGHGEC HCGECKCHAG YIGDNCNCST DISTCRGRDG QICSERGHCL CGQCQCTEPG AFGEMCEKCP TCPDACSTKR DCVECLLLHS GKPDNQTCHS LCRDEVITWV DTIVKDDQEA VLCFYKTAKD CVMMFTYVEL PSGKSNLTVL REPECGNTPN A Integrins are important extracellular matrix (ECM) receptor proteins located on cell surfaces
- They are hetrodimers composed of an alpha and a beta transmembrane glycoprotein subunit
- Around 22 different integrins (different alpha/ beta subunit combinations) are found in nature
- Integrins are generally present in high concentrations at the cell surface, but, unlike most other cell-surface receptors, they bind ligands with very low affinity
- Due to their weak individual binding, integrins need to cluster and bind in-groups in order to effectively bind the ECM
- Integrins bind many different ligands including laminin
- Each integrin is made up of a large N-terminal extracellular domain that binds the ECM ligand and a small C-terminal cytoplasmic domain that mediates interaction with the actin cytoskeleton and signaling function.