WISP2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5121104-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5121104 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
WISP2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CCN5
Gene Alias
CCN family member 5; CCN family protein COP-1; Ccn5; connective tissue growth factor-like protein; Connective tissue growth factor-related protein 58; Cop1; Crgr4; CT58; CTGFL; CTGF-L; Rcop1; UNQ228/PRO261; WISP2; WISP-2; WNT1 inducible signaling pathway protein 2; WNT1-inducible-signaling pathway protein 2
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22403, 29576, 8839
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1.16 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene Accession No.
O76076, Q9JHC6, Q9Z0G4
Gene Symbols
CCN5
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 164-250 of human WISP2 (NP_0038721)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: SKOV3, A-549, U2OS, Mouse heart
- The target is usually found in the following locations: Secreted
- Immunogen sequence: GQGGGLGTQP LPAQGPQFSG LVSSLPPGVP CPEWSTAWGP CSTTCGLGMA TRVSNQNRFC RLETQRRLCL SRPCPPSRGR SPQNSAF Wisp2 a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family
- WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes
- The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like (CT) domain
- Wisp2 lacks the CT domain which is implicated in dimerization and heparin binding
- It is 72% identical to the mouse protein at the amino acid level
- This gene may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation
- Its expression in colon tumors is reduced while the other two WISP members are overexpressed in colon tumors
- It is expressed at high levels in bone tissue, and may play an important role in modulating bone turnover.