PIPA5121143
NYX Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5121143-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5121143 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
NYX
Classification
Polyclonal
Conjugate
Unconjugated
Gene
NYX
Gene Alias
CLNP; CLRP; CSNB1; CSNB1A; CSNB4; leucine-rich repeat protein; NBM1; no b wave; nob; Nyctalopin; Nyx
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
236690, 60506
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
2.95 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
P83503, Q9GZU5
Gene Symbols
NYX
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 282-481 of human NYX (NP_072089.1).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: 293T
- The target is usually found in the following locations: Secreted, extracellular matrix, extracellular space
- Immunogen sequence: LLYLDRNSIA FVEEGAFQNL SGLLALHLNG NRLTVLAWVA FQPGFFLGRL FLFRNPWCCD CRLEWLRDWM EGSGRVTDVP CASPGSVAGL DLSQVTFGRS SDGLCVDPEE LNLTTSSPGP SPEPAATTVS RFSSLLSKLL APRVPVEEAA NTTGGLANAS LSDSLSSRGV GGAGRQPWFL LASCLLPSVA QHVVFGLQMD The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins
- Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB)
- CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity
- The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.