Phospho-c-Cbl (Tyr700) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5121300-Each-of-1 | In Stock | ₹ 44,811.50 |
PIPA5121300 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,811.50
GST (18%): ₹ 8,066.07
Total Price: ₹ 52,877.57
Antigen
Phospho-c-Cbl (Tyr700)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Cbl
Gene Alias
4732447J05Rik; Cas-Br-M (murine) ecotropic retroviral transforming sequence; Casitas B-lineage lymphoma; casitas B-lineage lymphoma proto-oncogene; CBL; Cbl proto-oncogene; Cbl proto-oncogene, E3 ubiquitin protein ligase; CBL2; Cbl-2; CBL-3; CBLC; c-Cbl; E3 ubiquitin-protein ligase CBL; FRA11B; fragile site, folic acid type, rare, fra(11)(q23.3); NSLL; oncogene CBL2; proto-oncogene c-Cbl; RGD1561386; RING finger protein 55; RING-type E3 ubiquitin transferase CBL; RNF55; RNF57; signal transduction protein CBL
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
867
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.09 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene Accession No.
P22681
Gene Symbols
Cbl
Immunogen
A synthetic phosphorylated peptide around Y700 of human CBL (NP_005179.2).
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Positive test controls include: Jurkat
- The target is usually found in the following locations: Cell membrane, Cytoplasm
- Immunogen sequence: TEYMT Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation
- Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed)
- Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation
- Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling.