GNA11 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5121954-Each-of-1 | In Stock | ₹ 17,346.10 |
PIPA5121954 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,346.10
GST (18%): ₹ 3,122.298
Total Price: ₹ 20,468.398
Antigen
GNA11
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GNA11
Gene Alias
Dsk7; E430025L19; FBH; FBH2; FHH2; g alpha-11; G protein subunit alpha 11; GA11; GNA11; Gna-11; G-protein subunit alpha-11; G-protein subunit GL2 alpha; Gq class; GTP-binding protein alpha-subunit; guanine nucleotide binding protein (G protein), alpha 11 (Gq class); guanine nucleotide binding protein alpha 11; guanine nucleotide binding protein, alpha 11; guanine nucleotide regulatory protein G alpha 11; guanine nucleotide-binding protein alpha 11; guanine nucleotide-binding protein alpha 11 subunit; guanine nucleotide-binding protein G(y) subunit alpha; Guanine nucleotide-binding protein subunit alpha-11; HHC2; HYPOC2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
2767
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
500 μg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
P29992
Gene Symbols
GNA11
Immunogen
Recombinant protein G Protein Alpha 11. The antigen corresponds to amino acid range 1-359 of the target protein.
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Heterotrimeric guanine nucleotide-binding proteins (G proteins) consist of α, β and γ subunits and mediate the effects of hormones, neurotransmitters, chemokines and sensory stimuli
- To date, over 20 known Gα subunits have been classified into four families, Gα(s), Gα(i/o), Gα(q) and Gα(12), based on structural and functional similarities (1,2)
- Phosphorylation of Tyr356 of Gα(q)/Gα(11) is essential for activation of the G protein, since phenylalanine substitution for Tyr356 changes the interaction of Gα with receptors and abolishes ligand-induced IP3 formation (3).