PIPA5122082
COL4A4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5122082-Each-of-1 | In Stock | ₹ 17,346.10 |
PIPA5122082 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 17,346.10
GST (18%): ₹ 3,122.298
Total Price: ₹ 20,468.398
Antigen
COL4A4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
COL4A4
Gene Alias
CA44; COL4A4; Collagen 4; Collagen alpha-4(IV) chain; Collagen IV, alpha-4 polypeptide; collagen of basement membrane, alpha-4 chain; collagen type IV alpha 4 chain; collagen, type IV, alpha 4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1286
Content And Storage
-20°C
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
P53420
Gene Symbols
COL4A4
Immunogen
Recombinant protein Collagen Type IV Alpha 4. The antigen corresponds to amino acid range 1469-1690 of the target protein.
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Collagens are highly conserved and are characterized by an uninterrupted Glycine-X-Y triplet repeat
- Col1, the fibrillar collagen found in most connective tissues, is the only component of the collagen found in cartilage
- Mutations in this gene are associated with osteogenesis imperfecta, Ehlers-Danlos syndrome, and idiopathic osteoporosis
- Col2, a fibrillar collagen found in cartilage and the vitreous humor of the eye
- Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia
- Col3 is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I collagen
- Mutations in this gene are associated with Ehlers-Danlos syndrome type IV, aortic and arterial aneurysms
- Col4 is a major consitiuent of the basement membranes along with laminins and enactins
- It is composed of alpha 1 IV chain and alpha 2 IV chain in 2:1 ratio
- Col4 antibodies are useful in detecting the loss of parts of basement membrane in carcinomas
- Col5 is found in tissues containing Col1 and appears to regulate the assembly of heterotypic fibers composed of both Col1 and Col5
- Col5 is closely related to type XI collagen; mutations in this gene are associated with Ehlers-Danlos syndrome.