PIPA5122141
CCS Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5122141-Each-of-1 | In Stock | ₹ 14,756.20 |
PIPA5122141 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,756.20
GST (18%): ₹ 2,656.116
Total Price: ₹ 17,412.316
Antigen
CCS
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CCS
Gene Alias
CCS; Ccsd; copper chaperone for superoxide dismutase; Superoxide dismutase copper chaperone
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9973
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
O14618
Gene Symbols
CCS
Immunogen
Recombinant protein Superoxide Dismutase, Copper Chaperone. The antigen corresponds to amino acid range 23-269 of the target protein.
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS)
- SOD catalyzes the dismutation reaction of superoxide radical anion (O2) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase
- Several classes of SOD have been identified
- These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3)
- SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit
- The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain
- SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways
- SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase
- CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor.