PIPA5122241
Angiopoietin 2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5122241-Each-of-1 | In Stock | ₹ 14,756.20 |
PIPA5122241 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 14,756.20
GST (18%): ₹ 2,656.116
Total Price: ₹ 17,412.316
Antigen
Angiopoietin 2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ANGPT2
Gene Alias
AGPT2; Ang2; Ang-2; angiopoietin 2; angiopoietin-2; angiopoietin-2a; angiopoietin-2B; ANGPT2; endothelial growth factor; Tie2-ligand
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
285
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300
Gene Accession No.
O15123
Gene Symbols
ANGPT2
Immunogen
Recombinant protein Angiopoietin 2. The antigen corresponds to amino acid range 24-165 of the target protein.
Quantity
20 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- ANG-2 binds to the endothelial cell specific receptor Tie-2, but, in contrast to ANG-1, does not induce tyrosine phosphorylation
- Consequently, ANG-2 modulates ANG-1 activation of Tie-2 and, depending on the physiological and biochemical environment, can act either as an agonist or antagonist of Tie-2 induced angiogenesis
- The signaling interactions of ANG-1, ANG-2 and Tie-2, along with less characterized ANG-3 and ANG-4, are required for embryonic and adult angiogenesis
- Physiologically, ANG-1 and ANG-2 are associated with sprouting, tube formation, and structural integrity of newly formed blood vessels
- Mature human ANG-2 is a secreted protein containing 480 amino acid residues
- ANG-2 is composed of an alpha-helix-rich coiled coil N-terminal domain and fibrinogen-like C-terminal domain
- ANG-2 exists predominantly in the form of a disulfide-linked dimer.