PIPA512564

Phospho-Cdc25A (Thr507) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA512564-Each-of-1 In Stock ₹ 48,905.50

PIPA512564 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

Phospho-Cdc25A (Thr507)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

CDC25A

Gene Alias

CDC25 isoform A1-CAG; CDC25A; CDC25A2; CDC25A2-CAG isoform; Cdc25m3; cell division cycle 25A; D9Ertd393e; dual specificity phosphatase Cdc25A; EC 3.1.3.48; M-phase inducer phosphatase 1; MPIP1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography, Protein A

Regulatory Status

RUO

Gene ID (Entrez)

993

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

P30304

Gene Symbols

CDC25A

Immunogen

KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T507 of human CDC25A

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with bovine, mouse and rat based on sequence homology
  • CDC25a is a member of the CDC25 family of phosphatases
  • Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C
  • These three genes function at different phases of the cell cycle
  • CDC25a is required for progression through G1 and S phases of the cell cycle
  • CDC25a activates the cyclin-dependent kinase CDC2 by removing two phosphate groups
  • CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division
  • CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated.