PIPA514044
DAPK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA514044-Each-of-1 | In Stock | ₹ 46,947.50 |
PIPA514044 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,947.50
GST (18%): ₹ 8,450.55
Total Price: ₹ 55,398.05
Antigen
DAPK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DAPK1
Gene Alias
D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
1612, 69635
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
2 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P53355, Q80YE7
Gene Symbols
DAPK1
Immunogen
KLH conjugated synthetic peptide between 1360-1389 amino acids from the C-terminal region of human DAPK1
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor
- DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy
- It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting
- Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent
- DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function
- It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.