Securin Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5141125-Each-of-1 | In Stock | ₹ 41,741.00 |
PIPA5141125 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,741.00
GST (18%): ₹ 7,513.38
Total Price: ₹ 49,254.38
Antigen
Securin
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Pttg1
Gene Alias
AW555095; C87862; EAP1; Esp1-associated protein; ESP1-associated protein 1; HPTTG; MGC126883; MGC138276; Pituitary tumor transforming; pituitary tumor-transforming 1; pituitary tumor-transforming gene 1; pituitary tumor-transforming gene 1 protein; PTTG; PTTG1; Pttg3; Securin; tumor-transforming protein 1; TUTR1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
9232
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Applications
Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene Accession No.
O95997
Gene Symbols
Pttg1
Immunogen
Recombinant protein within human Securin aa 2-202.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- The encoded protein is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation
- It is an anaphase-promoting complex (APC) substrate that associates with a separin until activation of the APC
- The gene product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors
- The gene product contains 2 PXXP motifs, which are required for its transforming and tumorigenic activities, as well as for its stimulation of basic fibroblast growth factor expression
- It also contains a destruction box (D box) that is required for its degradation by the APC
- The acidic C-terminal region of the encoded protein can act as a transactivation domain
- The gene product is mainly a cytosolic protein, although it partially localizes in the nucleus.