PIPA5142735

OXER1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5142735-Each-of-1 In Stock ₹ 40,317.00

PIPA5142735 - Each of 1

₹ 40,317.00

In Stock

Quantity

1

Base Price: ₹ 40,317.00

GST (18%): ₹ 7,257.06

Total Price: ₹ 47,574.06

Antigen

OXER1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

OXER1

Gene Alias

5-oxo-ETE acid G-protein-coupled receptor 1; 5-oxo-ETE G-protein coupled receptor; GPCR; GPR170; G-protein coupled receptor 170; G-protein coupled receptor R527; G-protein coupled receptor TG1019; HEOAD54; OXE receptor; OXER1; oxoeicosanoid (OXE) receptor 1; oxoeicosanoid receptor 1; TG1019

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

165140

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8TDS5

Gene Symbols

OXER1

Immunogen

Peptide with sequence C-SRQWRYREASRK.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000
  • TG1019 is a G protein-coupled receptor that functions as a chemoattractant for eosinophils and neutrophils
  • TG1019 is expressed in various tissues except the brain, with the highest expression in liver, kidney, peripheral leukocyte, lung and spleen
  • TG1019 interacts with the protein OXE to form TG1019/OXE, a Galpha i/o protein-coupled receptor
  • Signals from TG1019 are transduced via a Galpha i/o protein to PLC/calcium, MEK/ERK and PI3K/Akt pathways
  • Signal transduction from TG1019 following stimulation with 5-oxo-6E,8Z,11Z,14Z eicosatetraenoic acid (5-oxo-ETE) induces intracellular calcium mobilization and rapid activation of MEK/ERK and PI3K/Akt pathways
  • TG1019 also may play a role in downregulating cAMP production.