PIPA518510

PERP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA518510-Each-of-1 In Stock ₹ 46,591.50

PIPA518510 - Each of 1

₹ 46,591.50

In Stock

Quantity

1

Base Price: ₹ 46,591.50

GST (18%): ₹ 8,386.47

Total Price: ₹ 54,977.97

Antigen

PERP

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PERP

Gene Alias

1110017A08Rik; dJ496H19.1; HGNC:17637; KCP1; KCP-1; keratinocyte associated protein 1; keratinocyte-associated protein 1; keratinocytes associated protein 1; KRTCAP1; p53 apoptosis effector related to PMP22; p53 apoptosis effector related to PMP-22; p53 apoptosis-associated target; p53-induced protein PIGPC1; PERP; PERP, TP53 apoptosis effector; PIGPC1; RP3-496H19.1; THW; Transmembrane protein THW

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

64065

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q96FX8

Gene Symbols

PERP

Immunogen

Synthetic peptide sequence (CLPNYEDDLLGNAK) corresponding to the C-terminus amino acids of PERP

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • This antibody is predicted to react with canine, mouse and rat based on sequence homology
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000
  • The p53 tumor-suppressor gene integrates numerous signals that control cell life and death
  • Several novel molecules involved in p53 network, including Chk2, p53R2, p53AIP1, Noxa, PIDD, PID/MTA2, MTBP and PERP, were identified and their genes were cloned recently
  • PERP, also termed PIGPC1 and THW, is a plasma membrane protein
  • p53 binds to the promoter of PERP and transcriptionally activates PERP gene then the translated PERP protein mediates the p53 induced apoptosis
  • The expression of PERP causes cell death
  • PERP is a mediator of p53 induced apoptosis
  • PERP has sequence similarity to PMP-22/gas3 and is a new member of the PMP-22/gas3 family.