PIPA5142814
CD7 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142814-Each-of-1 | In Stock | ₹ 40,317.00 |
PIPA5142814 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,317.00
GST (18%): ₹ 7,257.06
Total Price: ₹ 47,574.06
Antigen
CD7
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CD7
Gene Alias
Cd7; CD7 antigen; CD7 antigen (p41); Cd7 molecule; GP40; LEU-9; p41 protein; T-cell antigen CD7; T-cell leukemia antigen; T-cell surface antigen Leu-9; Tp40; TP41
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
924
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
P09564
Gene Symbols
CD7
Immunogen
Peptide with sequence TEEQSQGWHRCSDAP.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
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Description
- Additional Information: The immunizing peptide corresponds to a part of the extracellular domain
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:32,000
- CD7 (gp40, Leu9) is a 40 kDa member of the immunoglobulin gene superfamily
- CD7 contains N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxy-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects
- CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia
- Further, CD7 is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells
- Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation
- CD7 associates directly with phosphoinositol 3'-kinase
- CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation
- Expression of CD7 is an important marker used in leukemia diagnostics.