PIPA5142882

NALP10 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5142882-Each-of-1 In Stock ₹ 40,317.00

PIPA5142882 - Each of 1

₹ 40,317.00

In Stock

Quantity

1

Base Price: ₹ 40,317.00

GST (18%): ₹ 7,257.06

Total Price: ₹ 47,574.06

Antigen

NALP10

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NLRP10

Gene Alias

6430548I20Rik; CLR11.1; NACHT, leucine rich repeat and PYD containing 10; NACHT, LRR and PYD containing protein 10; NACHT, LRR and PYD domains-containing protein 10; NACHT/LRR/pyrin domain-containing protein 10; NALP10; Napl10; neuronal apoptosis inhibitor protein 10; NLR family pyrin domain containing 10; NLR family, pyrin domain containing 10; NLRP10; NOD8; Nucleotide-binding oligomerization domain protein 8; nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 10; PAN5; Pynod

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

244202

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Flow Cytometry, Immunocytochemistry

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q8CCN1

Gene Symbols

NLRP10

Immunogen

Peptide with sequence NDLEENSFKTLKFH-C.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse

Form

Liquid

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000
  • NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction
  • Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain
  • It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1-b, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1-b processing, and ASC aggregation
  • NALP10 is thus a potent regulator of apoptosis and inflammation.