PIPA5142933

GPX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5142933-Each-of-1 In Stock ₹ 40,317.00

PIPA5142933 - Each of 1

₹ 40,317.00

In Stock

Quantity

1

Base Price: ₹ 40,317.00

GST (18%): ₹ 7,257.06

Total Price: ₹ 47,574.06

Antigen

GPX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

GPX1

Gene Alias

AI195024; AL033363; Cellular glutathione peroxidase; CGPx; cytosolic glutathione peroxidase; glutathione peroxidase; glutathione peroxidase 1; Gpx; Gpx1; GPx-1; GPXD; GSHPx; GSHPX1; GSHPx-1; HGNC:4553; MGC14399; MGC88245; OTTHUMP00000210766; Selenium-dependent glutathione peroxidase 1

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

14775, 24404

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

P04041, P11352

Gene Symbols

GPX1

Immunogen

Peptide with sequence C-DYTEMNDLQKRLGPR.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Mouse, Rat

Form

Liquid

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Description

  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000
  • Glutathione peroxidases (Gpxs) are ubiquitously expressed proteins which catalyze the reduction of hydrogen peroxides and organic hydroperoxides by glutathione
  • There are several isoforms which differ in their primary structure and localization
  • The classical cytosolic/mitochondrial GPx1 (cGPx) is a selenium-dependent enzyme, first of the GPx family to be discovered
  • GPx2, also known as gastrointestinal GPx (GI-GPx), is an intracellular enzyme expressed only at the epithelium of the gastrointestinal tract
  • Extracellular plasma GPx (pGPx or GPx3) is mainly expressed by the kidney from where it is released into the blood circulation
  • Phospholipid hydroperoxide GPx4 (PH-GPx) expressed in most tissues, can reduce many hydroperoxides including hydroperoxides integrated in membranes, hydroperoxy lipids in low density lipoprotein or thymine
  • All mammalian GPx family members, except for the recently described Cys containing GPx3 and epididymis-specific secretory GPx (eGPx or GPx5) isoforms, possess selenocysteine at the active site.