KIM-1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142968-Each-of-1 | In Stock | ₹ 40,317.00 |
PIPA5142968 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,317.00
GST (18%): ₹ 7,257.06
Total Price: ₹ 47,574.06
Antigen
KIM-1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Havcr1
Gene Alias
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
26762
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q96D42
Gene Symbols
Havcr1
Immunogen
Peptide with sequence C-THVTYRKDTRYK.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- Additional Information: The immunizing peptide represents part of the extracellular domain
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000
- CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail
- The endogenous ligand for CD365 is Tim-4
- In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus
- The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes
- Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity
- CD365 has also been implicated in the T cell co-stimulation
- CD365 is primarily expressed in epithelial cells
- It is also highly expressed in A549, 769-P and Caco-2 and cell lines
- CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.