PIPA5142996

THNSL2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5142996-Each-of-1 In Stock ₹ 40,317.00

PIPA5142996 - Each of 1

₹ 40,317.00

In Stock

Quantity

1

Base Price: ₹ 40,317.00

GST (18%): ₹ 7,257.06

Total Price: ₹ 47,574.06

Antigen

THNSL2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

THNSL2

Gene Alias

BC051244; FLJ10916; FLJ35504; RGD1309144; secreted osteoclastogenic factor of activated T cells; Secreted osteoclastogenic factor of activated T-cells; SOFAT; THNSL2; threonine synthase like 2; threonine synthase-like 2; threonine synthase-like 2 (bacterial); threonine synthase-like 2 (S. cerevisiae); THS2; TSH2

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

55258

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

Q86YJ6

Gene Symbols

THNSL2

Immunogen

Peptide with sequence C-SRFRHREVVHLSR.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

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Description

  • Additional Information: This antibody is expected to recognize isoform 1 (NP_060741.3) and isoform 2 (NP_001231605.1) only
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000
  • THNSL2 (threonine synthase-like 2), also known as TSH2, is a 484 amino acid protein belonging to the threonine synthase family
  • Utilizing pyridoxal phosphate as a cofactor, THNSL2 may function as a catabolic phospholyase on gamma and beta phosphorylated substrates
  • THNSL2 may also degrade O-phospho-threonine to alpha-ketobutyrate, ammonia and phosphate
  • Existing as four alternatively spliced isoforms, THNSL2 is encoded by a gene mapping to human chromosome 2p11.2
  • As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes
  • A number of genetic diseases are linked to genes on chromosome 2
  • Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene
  • The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8 gene defects
  • An extremely rare recessive genetic disorder, Alstrom syndrome, is related to mutations in the ALMS1 gene.