PTGES2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143284-Each-of-1 | In Stock | ₹ 40,317.00 |
PIPA5143284 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,317.00
GST (18%): ₹ 7,257.06
Total Price: ₹ 47,574.06
Antigen
PTGES2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Ptges2
Gene Alias
0610038H10Rik; C79137; C9orf15; FLJ14038; gamma-interferon-activated transcriptional element-binding factor 1; GATE-binding factor 1; Gbf1; GBF-1; membrane-associated prostaglandin E synthase 2; membrane-associated prostaglandin E synthase-2; MGC11289; Microsomal prostaglandin E synthase 2; microsomal prostaglandin E synthase-2; mPGE synthase-2; Mpges2; mPGES-2; PGES2; Prostaglandin E synthase 2; Prostaglandin E synthase 2 truncated form; Prostaglandin-H(2) E-isomerase; PTGES2; RP11-395P17.2
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
80142
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q9H7Z7
Gene Symbols
Ptges2
Immunogen
Peptide with sequence C-RLKSRHRLQDNVRED.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Related Products
Description
- Additional Information: This antibody is expected to recognize both reported isoforms (NP_079348.1; NP_945176.1)
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000
- Prostoglandin E2 (PGE2) is a potent lipid mediator produced by metabolism of arachidonic acid via the cyclooxygenase (COX) pathway
- Following cellular stimulation, arachidonic acid is hydrolyzed from phospholipids stores by one of a family of phospholipase A2 enzymes and converted to the unstable endoperoxide PGH2 by either COX 1 or COX 2
- PGH2 is isomerized to PGE2 by one of 3 distinct enzymes microsomal PGES 1 (mPGES 1), mPGES 2, or a cytosolic enzyme, cPGES
- PGE2 is active in a number of physiological systems and settings including inflammation, immune regulation, generation of fever, pain perception, protection of the gastric muscosa, fertility and parturition, as well as sodium and water retention
- The effects of PGE2 are transduced by 4 subtypes of G protein coupled receptors designated EP1, EP2, EP3, EP4, with Kd values for PGE2 ranging from 1 10 nM
- PGE2 is rapidly metabolized in vivo by the prostaglandin 15 dehydrogenase pathway (15 hydroxy PGDH) to the inactive metabolite 13,14 dihydro 15 keto PGE2
- The half life of PGE2 in the circulatory system is ∽30 seconds and normal plasma levels are 3 12 pg/mL