PIPA5143163

alpha Actinin 1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143163-Each-of-1 In Stock ₹ 40,317.00

PIPA5143163 - Each of 1

₹ 40,317.00

In Stock

Quantity

1

Base Price: ₹ 40,317.00

GST (18%): ₹ 7,257.06

Total Price: ₹ 47,574.06

Antigen

alpha Actinin 1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ACTN1

Gene Alias

3110023F10Rik; actinin; actinin 1 smooth muscle; actinin alpha 1; actinin, alpha 1; Actn1; Actn1a; alpha actinin 1a; alpha-actinin; alpha-actinin cytoskeletal isoform; Alpha-actinin-1; BDPLT15; F-actin cross-linking protein; fibroblast alpha actinin; FLJ40884; FLJ54432; hypothetical protein; hypothetical protein LOC524770; I79_004057; non-muscle alpha-actinin 1; non-muscle alpha-actinin-1

Host Species

Goat

Purification Method

Ammonium sulfate precipitation

Regulatory Status

RUO

Gene ID (Entrez)

109711, 81634, 87

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

0.5 mg/mL

Formulation

TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.

P12814, Q7TPR4, Q9Z1P2

Gene Symbols

ACTN1

Immunogen

Peptide with sequence C-TPQEINGKWDHVRQ.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • Additional Information: This antibody is expected to recognize all reported isoforms (NP_001123476.1; NP_001093.1; NP_001123477.1)
  • This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000
  • Alpha Actinin 1 belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins
  • Alpha actinin is an actin-binding protein with multiple roles in different cell types
  • In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane
  • In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments
  • This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene
  • Three transcript variants encoding different isoforms have been found for this gene.