PIPA5143577

MECP2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143577-Each-of-1 In Stock ₹ 42,675.50

PIPA5143577 - Each of 1

₹ 42,675.50

In Stock

Quantity

1

Base Price: ₹ 42,675.50

GST (18%): ₹ 7,681.59

Total Price: ₹ 50,357.09

Antigen

MECP2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Mecp2

Gene Alias

1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10

Host Species

Chicken

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgY

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Immunohistochemistry (PFA fixed), Western Blot

Concentration

Conc. Not Determined

Formulation

PBS with 5mM sodium azide

Gene Accession No.

P51608, Q00566, Q9Z2D6

Gene Symbols

Mecp2

Immunogen

Full length recombinant human MeCP2 expressed in and purified from E. coli.

Regulatory Status

RUO

Gene ID (Entrez)

17257, 29386, 4204

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Related Products

Img

Thermo Scientific

PIPA5143630

--

Img

Thermo Scientific

PIPA5143716

--

Img

Thermo Scientific

PIPA5143546

--

Img

Thermo Scientific

PIPA5143558

--

Img

Thermo Scientific

PIPA5143592

--

Img

Thermo Scientific

PIPA5143523

--

Img

Thermo Scientific

PIPA5143616

--

Img

Thermo Scientific

PIPA5143518

--

Description

  • MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain
  • MECP2 is capable of binding specifically to methylated DNA
  • DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
  • MECP2 can also repress transcription from methylated gene promoters
  • In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation
  • MECP2 is dispensible in stem cells, but is essential for embryonic development
  • MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.