Phospho-MECP2 (Ser80) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143630-Each-of-1 | In Stock | ₹ 35,422.00 |
PIPA5143630 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 35,422.00
GST (18%): ₹ 6,375.96
Total Price: ₹ 41,797.96
Antigen
Phospho-MECP2 (Ser80)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Mecp2
Gene Alias
1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10
Host Species
Rabbit
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
Applications
Immunohistochemistry (Frozen), Western Blot
Concentration
Lot-Specific
Formulation
Serum with no preservative
Gene Accession No.
P51608, Q00566, Q9Z2D6
Gene Symbols
Mecp2
Immunogen
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser80 of human MeCP2, conjugated to keyhole limpet hemocyanin (KLH).
Regulatory Status
RUO
Gene ID (Entrez)
17257, 29386, 4204
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG
Related Products
Description
- Specific for endogenous levels of the ∽75 kDa MeCP2 protein phosphorylated at Ser80 in Western blots of human, rat and mouse brain extracts
- The antibody has also been used successfully for immunohistochemistry on mouse brain sections
- MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain
- MECP2 is capable of binding specifically to methylated DNA
- DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development
- MECP2 can also repress transcription from methylated gene promoters
- In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation
- MECP2 is dispensible in stem cells, but is essential for embryonic development
- MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.