PIPA5143745

Plexin-A1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143745-Each-of-1 In Stock ₹ 45,879.50

PIPA5143745 - Each of 1

₹ 45,879.50

In Stock

Quantity

1

Base Price: ₹ 45,879.50

GST (18%): ₹ 8,258.31

Total Price: ₹ 54,137.81

Antigen

Plexin-A1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PLXNA1

Gene Alias

2600013D04Rik; Kiaa4053; mKIAA4053; NOV; NOVP; Plex 1; PlexA1; plexin 1; plexin A1; plexin-1; plexin-A1; PLXN1; Plxna1; RGD1560871; semaphorin receptor NOV

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

18844, 362398, 5361

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P70206, Q9UIW2

Gene Symbols

PLXNA1

Immunogen

Plexin-A1 synthetic peptide (coupled to carrier protein) corresponding to a region within the N-terminal half of the semaphorin domain in human Plexin-A1. This sequence is highly conserved in rat and mouse Plexin-A1, and has low homology to other Plexin family members.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • The antibody detects a 220 kDa* protein corresponding to the apparent molecular mass of Plexin-A1 on SDS-PAGE immunoblots of neonatal rat brain and Cos-7 cells transfected with mouse Plexin-A1
  • In immunocytochemistry, this antibody co-localizes with anti-Myc in Cos-7 cells transfected with Myc-tagged mouse Plexin-A1
  • Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D
  • Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton
  • Plays a role in axon guidance, invasive growth and cell migration
  • Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin
  • The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm
  • [UniProt]