VEGF Receptor 2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5143790-Each-of-1 | In Stock | ₹ 39,961.00 |
PIPA5143790 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,961.00
GST (18%): ₹ 7,192.98
Total Price: ₹ 47,153.98
Antigen
VEGF Receptor 2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
KDR
Gene Alias
6130401C07; CD309; CD309 antigen; fetal liver kinase 1; fetal liver kinase-1; FLK1; Flk-1; FLK1 kinase insert domain receptor (a type III receptor tyrosine kinase) (VEGF receptor 2); FLK1 kinase insert domain receptor (VEGF receptor 2); flk-1 type VEGF receptor; KDR; kinase insert domain protein receptor; kinase insert domain receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); kinase NYK; Krd-1; Ly73; protein-tyrosine kinase receptor flk-1; sCD309; soluble CD309; soluble vascular endothelial growth factor receptor 2; soluble VEGFR 2; soluble VEGFR2; sVEGFR-2; tyrosine kinase growth factor receptor; vascular endotheial growth factor 2; vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor- 2; vascular endothelial growth factor receptor-2; vascular endothelial growth factor receptor-3; VEGF R2; VEGF receptor-2; VEGFR; VEGFR2; VEGFR-2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
16542, 25589, 3791
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Immunocytochemistry, Western Blot
Concentration
Lot-Specific
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
O08775, P35918, P35968
Gene Symbols
KDR
Immunogen
A synthetic peptide (coupled to carrier protein) corresponding to amino acids from the N-terminal region of human VEGFR-2. This sequence has high homology to rat and mouse VEGFR-2, and no significant homology to other VEGFR family members.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Liquid
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Description
- The antibody detects a 180 kDa* band corresponding to VEGFR-2 in western blots of human endothelial cells, and shows strong reactivity toward recombinant human VEGFR-2, but not VEGFR-1 or VEGFR-3
- The antibody also works for immunofluorescent staining of VEGFR-2 in HUVEC cells
- KDR (FLK1, VEGFR2) is a type III receptor tyrosine kinase
- It binds vascular endothelial growth factor with high affinity in vitro, and is expressed early in development by endothelial cell precursors
- FLK1 (VEGF Receptor 2) encodes one of the two receptors of the VEGF
- This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase
- The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc
- Mutations of FLK1 (VEGF Receptor 2) are implicated in infantile capillary hemangiomas.