PIPA5143889

WWC1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143889-Each-of-1 In Stock ₹ 35,422.00

PIPA5143889 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

WWC1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

WWC1

Gene Alias

AA408228; AU017197; BC037006; FLJ10865; FLJ23369; HBeAg-binding protein 3; HBEBP3; HBEBP36; Kiaa0869; KIBRA; Kidney and brain protein; MEMRYQTL; mKIAA0869; PPP1R168; Protein KIBRA; protein phosphatase 1, regulatory subunit 168; protein WWC1; RGD1308329; WW and C2 domain containing 1; WW domain-containing protein 1; WW, C2 and coiled-coil domain containing 1; WWC1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

211652, 23286, 303039

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and 0.01MG sodium azide

Gene Accession No.

Q5SXA9, Q8IX03

Gene Symbols

WWC1

Immunogen

E.coli-derived human KIBRA/WWC1 recombinant protein (Position: D990-Q1080).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Lyophilized

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Description

  • Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
  • WWC1 (Protein KIBRA) is a probable regulator of the Hippo/SWH signaling pathway
  • This pathway plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis
  • WWC1, along with NF2, can synergistically induce the phosphorylation of LATS1 and LATS2
  • It acts as a transcriptional coactivator of ESR1 - which plays an essential role in DYNLL1-mediated ESR1 transactivation
  • WWC1 also functions as a regulatior of collagen-stimulated activation of the ERK/MAPK cascade.