PIPA5143912

UGT1A3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143912-Each-of-1 In Stock ₹ 35,422.00

PIPA5143912 - Each of 1

₹ 35,422.00

In Stock

Quantity

1

Base Price: ₹ 35,422.00

GST (18%): ₹ 6,375.96

Total Price: ₹ 41,797.96

Antigen

UGT1A3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

UGT1A3

Gene Alias

GNT1; polypeptide A3; UDP glucuronosyltransferase 1 family; UDP-glucuronosyltransferase 1A3; UGT1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

396551, 54659

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

500 μg/mL

Formulation

PBS with 4MG trehalose and no preservative

Gene Accession No.

P35503, Q64637

Gene Symbols

UGT1A3

Immunogen

E.coli-derived human UGT1A3 recombinant protein (Position: H92-C128).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Lyophilized

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Description

  • Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL
  • UDP-glucuronosyltransferase 1-3 is an enzyme that in humans is encoded by the UGT1A3 gene
  • This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites
  • This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases
  • The locus includes thirteen unique alternate first exons followed by four common exons
  • Four of the alternate first exons are considered pseudogenes
  • Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini
  • Each first exon encodes the substrate binding site, and is regulated by its own promoter
  • Substrates of this enzyme include estrone, 2-hydroxyestrone, and metabolites of benzo alpha-pyrene.