PPP6C Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA515607-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA515607 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
PPP6C
Classification
Polyclonal
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
O00743
Gene Symbols
Ppp6c
Immunogen
KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PPP6C
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Immunohistochemistry (Paraffin), Western Blot
Conjugate
Unconjugated
Gene
Ppp6c
Gene Alias
2310003C10Rik; ANKRD33; FLJ34236; PP6; PP6C; PPP6; PPP6C; Ppv; PP-V; protein phosphatase 6 catalytic subunit; protein phosphatase 6, catalytic subunit; protein phosphatase V; serine/threonine protein phosphatase catalytic subunit; serine/threonine-protein phosphatase 6 catalytic subunit; Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed; UNQ5837
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
5537
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Related Products
Description
- Distinct DNA repair pathways minimize the consequences of mutagenic events
- Reactive oxygen species (ROS) are highly reactive atoms with an unpaired electron that are conducive to double-strand DNA breaking events
- Artemis, named after the Greek goddess for the protection of children, is one of the major proteins contributing to the preservation of double-strand breaks in DNA by cutting away the damaged parts of the DNA, which allows the strands to rejoin
- Artemis is a single-strand-specific 5' to 3' exonuclease that forms a complex with the 469 kDa DNA-dependent protein kinase (DNA-PKcs)
- DNA-PKcs phosphorylates Artemis, and Artemis acquires endonucleolytic activity on 5' and 3' overhangs and hairpins
- These activities are essential for V(D)J recombination and for the 5' and 3' overhang processing in nonhomologous DNA end joining.