PPM1F Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA515571-Each-of-1 | In Stock | ₹ 48,905.50 |
PIPA515571 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,905.50
GST (18%): ₹ 8,802.99
Total Price: ₹ 57,708.49
Antigen
PPM1F
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PPM1F
Gene Alias
1110021B16Rik; 4933427B07Rik; Ca(2+)/calmodulin-dependent protein kinase phosphatase; calcium/calmodulin-dependent protein kinase phosphatase; caM-kinase phosphatase; CAMKP; CaMKPase; FEM-2; hFem-2; KIAA0015; mKIAA0015; Partner of PIX 2; partner of PIX2; POPX2; PP2C phosphatase; Ppm1f; Protein fem-2 homolog; protein phosphatase 1F; protein phosphatase 1F (PP2C domain containing); protein phosphatase, Mg2+/Mn2+ dependent 1F; protein phosphatase, Mg2+/Mn2+ dependent, 1F
Host Species
Rabbit
Purification Method
Ammonium sulfate precipitation, Size-exclusion - Dialysis
Regulatory Status
RUO
Gene ID (Entrez)
68606, 9647
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.09% sodium azide
Gene Accession No.
P49593, Q8CGA0
Gene Symbols
PPM1F
Immunogen
KLH conjugated synthetic peptide between 11-40 amino acids from the N-terminal region of human PPM1F
Quantity
400 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- PPM1F is a member of the PP2C family of Ser/Thr protein phosphatases
- PP2C family members are known to be negative regulators of cell stress response pathways
- This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases
- Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase
- The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis.