CDT1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA517024-Each-of-1 | In Stock | ₹ 42,853.50 |
PIPA517024 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,853.50
GST (18%): ₹ 7,713.63
Total Price: ₹ 50,567.13
Antigen
CDT1
Classification
Polyclonal
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
Q9H211
Gene Symbols
CDT1
Immunogen
Synthetic peptide corresponding to the amino terminal sequence of human CDT1
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Applications
Western Blot
Conjugate
Unconjugated
Gene
CDT1
Gene Alias
2610318F11Rik; AW545653; C76791; CDT1; chromatin licensing and DNA replication factor 1; DNA replication factor Cdt1; Double parked homolog; Double parked, Drosophila, homolog of; DUP; Retroviral insertion site 2 protein; retroviral integration site 1; retroviral integration site 2; RIS2
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
81620
Content And Storage
-20°C
Form
Liquid
Related Products
Description
- It is not recommended to aliquot this antibody
- KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis
- It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac)
- In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation
- KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity
- It has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', and has higher activity toward H3 acetylated on 'Lys-9'
- Required for transcriptional activation of HOXA9 and promotes PPP1R15A-induced apoptosis.