PIPA517384

TOLLIP Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517384-Each-of-1 In Stock ₹ 40,406.00

PIPA517384 - Each of 1

₹ 40,406.00

In Stock

Quantity

1

Base Price: ₹ 40,406.00

GST (18%): ₹ 7,273.08

Total Price: ₹ 47,679.08

Antigen

TOLLIP

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

Q9H0E2

Gene Symbols

TOLLIP

Immunogen

Synthetic peptide corresponding to residues surrounding cysteine 229 of human Tollip

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Non-human Primate

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

TOLLIP

Gene Alias

4930403G24Rik; 4931428G15Rik; adapter protein; EMBL:AAI33068.1}; FLJ33531; IL-1RAcPIP; toll interacting protein; toll-interacting protein; TOLLIP; tollip {ECO:0000312

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

54472

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila
  • These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses
  • The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection
  • These adaptor molecules include TOLLIP, MyD88, and TRIF
  • TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation
  • This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.