PIPA585492
TLR7 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585492-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA585492 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TLR7
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TLR7
Gene Alias
RGD1563357, RP23-139P21.3, Tlr7, TLR7-like, toll like receptor 7, toll-like receptor 7, toll-like receptor 7-like, UNQ248/PRO285
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
51284
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.
Q9NYK1
Gene Symbols
TLR7
Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human TLR7.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Mouse (81%), Rat (84%), Dog (82%), Cat (84%), Pig (81%), Sheep (85%), Rhesus Monkey (96%), Chimpanzee (100%), Bovine (86%)
- Positive Control: 293T transfected recombinant TLR7 protein
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- TLR7 is a 10 amino acid long highly conserved membrane protein belonging to the Toll-like receptor (TLR) family with 27 LRR (leucine-rich) repeats and a TIR domain
- TLR7 plays a fundamental role in pathogen recognition and activation of innate immunity
- TLR7 is activated by infections with single-stranded RNA viruses, including influenza virus and vesicular stomatitis virus (VSV)
- TLR7 is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8
- TLR7 also acts via MyD88 and TRAF6, leading to NF-kappaB activation, cytokine secretion and the inflammatory response
- TLR7 recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity.