beta Dystroglycan Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA519731-Each-of-1 | In Stock | ₹ 52,332.00 |
PIPA519731 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 52,332.00
GST (18%): ₹ 9,419.76
Total Price: ₹ 61,751.76
Antigen
beta Dystroglycan
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DAG1
Gene Alias
156DAG; A3a; AGRNR; Alpha-DG; Alpha-dystroglycan; Beta-DG; Beta-dystroglycan; D9Wsu13e; DAG; DAG1; Dag-1; DG; Dp427; Dp71; dystroglycan; dystroglycan 1; dystroglycan 1 (dystrophin-associated glycoprotein 1); dystrophin associated glycoprotein 1; Dystrophin-associated glycoprotein 1; MDDGA9; MDDGC7; MDDGC9
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1605
Content And Storage
-20°C or -80°C if preferred
Form
Liquid
Applications
Western Blot
Concentration
1.0 mg/mL
Formulation
PBS with 1% BSA and 0.02% sodium azide; pH 7.4
Gene Accession No.
Q14118
Gene Symbols
DAG1
Immunogen
Synthetic peptide conjugated to KLH derived from within residues 650 - 750 of Human Dystroglycan precursor.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- This antibody is predicted to react with mouse, rabbit, cow and dog based on sequence homology
- Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix
- Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies
- The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis
- Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane
- The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence
- Alternative splicing results in multiple transcript variants all encoding the same protein.