ACE2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520040-Each-of-1 | In Stock | ₹ 47,392.50 |
PIPA520040 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,392.50
GST (18%): ₹ 8,530.65
Total Price: ₹ 55,923.15
Antigen
ACE2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ACE2
Gene Alias
2010305L05Rik; ACE 2; Ace2; ACEH; ACE-related carboxypeptidase; angiotensin I converting enzyme (peptidyl-dipeptidase A) 2; angiotensin I converting enzyme 2; angiotensin-converting enzyme 2; Angiotensin-converting enzyme homolog; anigotensin I converting enzyme 2; anigotensin-converting enzyme-related carboxypeptidase; metalloprotease MPROT15; peptidyl-dipeptidase A; Processed angiotensin-converting enzyme 2; renal angiotensin-converting enzyme 2; UNQ868/PRO1885
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
302668, 59272, 70008
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q5EGZ1, Q8R0I0, Q9BYF1
Gene Symbols
ACE2
Immunogen
A synthetic peptide corresponding to amino acids near the C-terminus of human ACE2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- In Western blot applications, this antibody detects a band at ∽90kDa
- A suggested positive control is human kidney tissue lysate
- PA5-20040 can be used with blocking peptide PEP-0159
- Angiotensin-converting enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology
- In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis
- Recently
- ACE2 has also been shown to be a functional receptor of the SARS coronavirus
- The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII
- While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.