PIPA520049

TRIM5 alpha Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520049-Each-of-1 In Stock ₹ 46,502.50

PIPA520049 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TRIM5 alpha

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Trim5

Gene Alias

EG667823; Gm8833; HGNC:16276; OTTHUMP00000069812; RING finger protein 88; RING-type E3 ubiquitin transferase TRIM5; RNF88; TRIM5; Trim5 alpha; TRIM5 alpha; predicted E3 ubiquiting ligase; TRIM5 gamma; predicted E3 ubiquiting ligase; trim5a; TRIM5alpha; tripartite motif containing 5; tripartite motif containing 5 transcript variant iota; tripartite motif containing 5 transcript variant kappa; tripartite motif protein TRIM5; tripartite motif-containing 5; tripartite motif-containing 5 alpha isoform; tripartite motif-containing 5 gamma isoform; tripartite motif-containing 5/cyclophilin A fusion protein; tripartite motif-containing protein 5; tripartite motif-containing protein 5 isoform alpha

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

85363

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q9C035

Gene Symbols

Trim5

Immunogen

A synthetic peptide corresponding to amino acids near the mid-region of human TRIM5 alpha.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • In Western blot applications, this antibody detects a band at ∽55kDa
  • A suggested positive control is human stomach tissue lysate
  • PA5-20049 can be used with blocking peptide PEP-0168
  • The protein encoded by this gene is a member of the tripartite motif family
  • The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region
  • The protein forms homo-oligomers via the coiled-coil region and localizes to cytoplasmic bodies
  • It appears to function as a E3 ubiquitin-ligase and ubiquitinates itself to regulate its subcellular localization
  • It may play a role in retroviral restriction
  • Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.