PIPA520205
TOLLIP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520205-Each-of-1 | In Stock | ₹ 47,392.50 |
PIPA520205 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,392.50
GST (18%): ₹ 8,530.65
Total Price: ₹ 55,923.15
Antigen
TOLLIP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TOLLIP
Gene Alias
4930403G24Rik; 4931428G15Rik; adapter protein; EMBL:AAI33068.1}; FLJ33531; IL-1RAcPIP; toll interacting protein; toll-interacting protein; TOLLIP; tollip {ECO:0000312
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
361677, 54472, 54473
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
A2RUW1, Q9H0E2, Q9QZ06
Gene Symbols
TOLLIP
Immunogen
A 16 amino acid peptide from near the center of human TOLLIP.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is rat brain tissue lysate
- PA5-20205 can be used with blocking peptide PEP-0331
- Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila
- These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses
- The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection
- These adaptor molecules include TOLLIP, MyD88, and TRIF
- TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation
- This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.