PIPA520320
TSLP Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520320-Each-of-1 | In Stock | ₹ 49,439.50 |
PIPA520320 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,439.50
GST (18%): ₹ 8,899.11
Total Price: ₹ 58,338.61
Antigen
TSLP
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TSLP
Gene Alias
Thymic stroma-derived lymphopoietin; thymic stromal lymphopoietin; TSLP
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
53603, 85480
Content And Storage
4° C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q969D9, Q9JIE6
Gene Symbols
TSLP
Immunogen
A 19 amino acid peptide from near the center of human TSLP.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Despite its predicted molecular weight, TSLP often migrates at a higher molecular weight in SDS-PAGE
- A suggested positive control is A-20 cell lysate
- PA5-20320 can be used with blocking peptide PEP-0440
- TSLP is a 159 amino acid four helix-bundle hemopoietic cytokine that signals through a heterodimeric receptor complex consisting of the human TSLP receptor and the IL-7R alpha-chain
- It impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes, enhances the maturation of CD11c (+) dendritic cells, naive CD4 (+), and CD8 (+) T cells into proallergic effectors, and primes dendritic cells to produce large amounts of IL-12 after CD40 ligand stimulation
- TSLP influences the regulation of the positive selection of regulatory T cells and maintenance of peripheral CD4 (+) T cell homeostasis
- It induces allergic inflammation by directly activating mast cells and may be involved in the pathophysiology of inflammatory arthritis
- It is expressed in heart, liver and prostate.