PIPA520475

RIM3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520475-Each-of-1 In Stock ₹ 49,350.50

PIPA520475 - Each of 1

₹ 49,350.50

In Stock

Quantity

1

Base Price: ₹ 49,350.50

GST (18%): ₹ 8,883.09

Total Price: ₹ 58,233.59

Antigen

RIM3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RIMS3

Gene Alias

A730060M23Rik; KIAA0237; mKIAA0237; Nim2; NIM3; Rab-3 interacting molecule 3; rab-3-interacting molecule 3; regulating synaptic membrane exocytosis 3; regulating synaptic membrane exocytosis protein 3; RIM 3; RIM3; RIM3 gamma; Rims3; RP4-739H11.2; si:ch211-239d6.1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

242662, 9783

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q80U57, Q9UJD0

Gene Symbols

RIMS3

Immunogen

A 17 amino acid peptide from near the amino terminus of human Rim3.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is human brain tissue lysate
  • PA5-20475 can be used with blocking peptide PEP-0595
  • Rab3-interacting molecules (RIMs) are synaptic proteins are synaptic proteins necessary for neural transmission and plasticity
  • While both Rim1 and Rim 2 are thought to be effector proteins for Rab3, binding to Rab3 on synaptic vesicles in a GTP-dependent manner, less is known of Rim3
  • Expression of Rim3 in PC12 cells induced a significant increase in calcium-triggered exocytosis, with no appreciable change in the baseline release, suggesting that it plays a role in the regulation of exocytosis
  • Rim3 protein localizes primarily to neuronal dendrites and the postsynaptic densities, as opposed to Rim1 which is found in presynapse locations, indicating that Rim3 may contribute to synapse transmission and plasticity.