AIFM3 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520502-Each-of-1 | In Stock | ₹ 46,591.50 |
PIPA520502 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,591.50
GST (18%): ₹ 8,386.47
Total Price: ₹ 54,977.97
Antigen
AIFM3
Classification
Polyclonal
Conjugate
Unconjugated
Gene
AIFM3
Gene Alias
2810401C16Rik; AI840249; Aifl; AIFM3; apoptosis inducing factor, mitochondria associated 3; apoptosis-inducing factor 3; apoptosis-inducing factor like; apoptosis-inducing factor, mitochondrion-associated 3; apoptosis-inducing factor, mitochondrion-associated, 3; apoptosis-inducing factor-like protein; RGD1306028
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
150209, 303786, 72168
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q3TY86, Q96NN9
Gene Symbols
AIFM3
Immunogen
A 16 amino acid peptide from near the amino terminus of human AIFM3.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is mouse brain tissue lysate
- PA5-20502 can be used with blocking peptide PEP-0622
- Apoptosis, also known as programmed cell death, plays major roles in development and normal tissue turnover in addition to tumor formation
- Recently a protein similar to the apoptosis-inducing factor (AIF) was cloned and designated AIFL (also known as AIFM3)
- AIFM3 is expressed ubiquitously and is predominantly localized to the inner membranes of mitochondria
- Unlike AIF, AIFM3 does not translocate to the nucleus upon induction of apoptosis
- However, overexpression of AIFM3, like AIF, induced cytochrome c release from the mitochondria, cleavage of caspase 3, and μgtimately apoptosis, indicating AIFM3 induces apoptosis through caspase activation
- Multiple isoforms of AIFM3 are known to exist.