TMC6 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520505-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA520505 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
TMC6
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TMC6
Gene Alias
D11Ertd204e; epidermodysplasia verruciformis 1; epidermodysplasia verruciformis protein 1; EV1; EVER1; EVIN1; expressed in activated T/LAK lymphocytes; LAK-4P; protein LAK-4; Tmc6; transmembrane channel like 6; transmembrane channel-like gene family 6; transmembrane channel-like protein 6
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11322, 217353
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q7TN60, Q7Z403
Gene Symbols
TMC6
Immunogen
A 15 amino acid peptide from near the center of human EVER1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is human spleen tissue lysate
- PA5-20505 can be used with blocking peptide PEP-0625
- TMC6 interacts with, and forms a complex with the zinc transporter 1, SLC30A1, and localizes to the endoplasmic reticulum, nuclear membrane and Golgi apparatus
- The inactivation of the TMC6 gene has been implicated in the skin disorder epidermodysplasia verruciformis (EV), an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin
- EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3
- TMC6 encodes integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels
- This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs
- Diseases associated with TMC6 include Epidermodysplasia Verruciformis and Superficial Mycosis.