Lass5 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520647-Each-of-1 | In Stock | ₹ 46,413.50 |
PIPA520647 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,413.50
GST (18%): ₹ 8,354.43
Total Price: ₹ 54,767.93
Antigen
Lass5
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CERS5
Gene Alias
2310081H14Rik; AU045339; AW544927; Ceramide synthase 5; CerS5; LAG1 homolog, ceramide synthase 5; LAG1 longevity assurance homolog 5; LASS5; longevity assurance homolog 5; Sphingosine N-acyltransferase CERS5; TRAM homolog 4; translocating chain-associating membrane protein homolog 4; Trh4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
366984, 71949, 91012
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q8N5B7, Q9D6K9
Gene Symbols
CERS5
Immunogen
A 14 amino acid peptide near the amino terminus of the human LASS5.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is SK-N-SH cell lysate
- PA5-20647 can be used with blocking peptide PEP-0767
- The LASS (longevity assurance homolog) family members represent a subgroup of the homeobox gene family and are highly conserved from yeasts to mammals
- Six members of this family of proteins have been characterized (LASS1-6) and all are involved in ceramide synthesis during cell growth regulation and cancer differentiation
- LASS5, also called Trh4, is a 392 amino acid endoplasmic reticulum, multi-pass membrane protein
- Functioning as a dihydro-ceramide synthase, LASS5 is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked palmitoyl-ceramide) in a fumonisin B1-independent manner
- It uses palmitoyl-CoA as an acyl donor and is involved in the synthesis of C14, C16 and C18-ceramide
- LASS5 is the most abundantly expressed and predominant ceramide synthase isoform in lung epithelia
- Recent studies show that LASS5 partially correct growth and apoptosis.