UCMA Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520768-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA520768 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
UCMA
Classification
Polyclonal
Conjugate
Unconjugated
Gene
UCMA
Gene Alias
1110017I16Rik; AW121955; C10orf49; Gla-rich protein; GRP; GRP/UCMA; RGD1308977; Ucma; ucma {ECO:0000250; Ucma-C; UniProtKB:Q14BU0}; Unique cartilage matrix-associated protein; unique cartilage matrix-associated protein {ECO:0000250; Unique cartilage matrix-associated protein C-terminal fragment; upper zone of growth plate and cartilage matrix associated; upper zone of growth plate and cartilage matrix associated protein
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
221044, 68527
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q14BU0, Q8WVF2
Gene Symbols
UCMA
Immunogen
A 16 amino acid peptide near the carboxy terminus of human UCMA.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is SW1353 cell lysate
- PA5-20768 can be used with blocking peptide PEP-0882
- UCMA is a gene that encodes for a protein that is specific to chondrocytes and highly charged
- This protein is expressed abundantly in the upper immature zone of fetal and juvenile epiphyseal cartilage
- The encoded protein undergoes proteolytic processing to generate a mature protein that is secreted into the extracellular matrix
- The glutamic acid residues in the protein undergo gamma carboxylation in a vitamin K-dependent manner
- Undercarboxylation of the protein has been associated with osteoarthritis in humans
- Alternative splicing of the gene results in multiple transcript variants that encode different isoforms
- UCMA is also associated with diseases such as Osteoarthritis and Poland Syndrome.