PIPA520865

PPAPDC2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520865-Each-of-1 In Stock ₹ 46,413.50

PIPA520865 - Each of 1

₹ 46,413.50

In Stock

Quantity

1

Base Price: ₹ 46,413.50

GST (18%): ₹ 8,354.43

Total Price: ₹ 54,767.93

Antigen

PPAPDC2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PLPP6

Gene Alias

4932443D16Rik; bA6J24.6; FLJ46512; FLJ90191; MGC15483; PDP1; phosphatidic acid phosphatase type 2 domain containing 2; phosphatidic acid phosphatase type 2 domain-containing protein 2; Phospholipid phosphatase 6; PLPP6; polyisoprenoid diphosphate phosphatase type 1; PPAP2 domain-containing protein 2; Ppapdc2; Presqualene diphosphate phosphatase; PSDP; RP11-6J24.2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

403313, 619549, 74411

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q66H88, Q8IY26, Q9D4F2

Gene Symbols

PLPP6

Immunogen

A 13 amino acid peptide from near the carboxy terminus human PPAPDC2.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is Raji cell lysate
  • PA5-20865 can be used with blocking peptide PEP-0979
  • PPAPDC2 is a phosphatase that dephosphorylates Presqualene diphosphate (PSDP) into presqualene monophosphate (PSMP), suggesting that it may have important role in innate immunity
  • PSDP is a bioactive lipid that rapidly remodels to PSMP upon cell activation
  • PPAPDC2 displays diphosphate phosphatase activity with a substrate preference for PSDP > FDP > phosphatidic acid
  • PPAPDC2 activity is independent of Mg2+ and has been identified in activated human neutrophil (PMN) extracts
  • It is widely expressed in human tissues
  • Recent studies shows PPAPDC2 is a functional isoprenoid diphosphate phosphatase.