PPAPDC1B Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520881-Each-of-1 | In Stock | ₹ 46,057.50 |
PIPA520881 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,057.50
GST (18%): ₹ 8,290.35
Total Price: ₹ 54,347.85
Antigen
PPAPDC1B
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PLPP5
Gene Alias
1810019D05Rik; 2310022A04Rik; AW045471; diacylglycerol pyrophosphate like 1; diacylglycerol pyrophosphate phosphatase-like 1; DPPL1; HTPAP; phosphatidate phosphatase PPAPDC1B; phosphatidic acid phosphatase type 2 domain containing 1; phosphatidic acid phosphatase type 2 domain containing 1B; phosphatidic acid phosphatase type 2 domain-containing protein 1B; Phospholipid phosphatase 5; Plpp5; Ppapdc1; Ppapdc1b; testicular secretory protein Li 38
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
71910, 84513
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
Q3UMZ3, Q8NEB5
Gene Symbols
PLPP5
Immunogen
A 14 amino acid peptide near the amino terminus of human PPAPDC1B.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is EL4 cell lysate
- PA5-20881 can be used with blocking peptide PEP-0995
- Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells
- Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide (NEM) and Mg2+
- A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated
- PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity
- Knockdown experiments indicated that this protein is involved with multiple cell signaling pathways, including the JAK-Stat3, MAP kinase, and PKC pathways
- PPAPDC1B may also potentiate the estrogen receptor pathway by down-regulating DUSP22.