PIPA520895
CALHM1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520895-Each-of-1 | In Stock | ₹ 46,502.50 |
PIPA520895 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 46,502.50
GST (18%): ₹ 8,370.45
Total Price: ₹ 54,872.95
Antigen
CALHM1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Calhm1
Gene Alias
calcium homeostasis modulator 1; calcium homeostasis modulator protein 1; Calhm1; EG546729; Fam26c; family with sequence similarity 26, member C; Protein FAM26C; RGD1564891
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
255022, 499367, 546729
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunohistochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
D3Z291, Q8IU99
Gene Symbols
Calhm1
Immunogen
A 17 amino acid peptide near the amino terminus of human CALHM1.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- A suggested positive control is rat liver tissue lysate
- PA5-20895 can be used with blocking peptide PEP-1009
- Alzheimers disease (AD) is a progressive neurodegenerative disorder characterized by a massive loss of neurons in several brain regions and by the presence of senile plaques comprised of aggregated amyloid-beta (Abeta) peptides produced by the endoproteolysis of the amyloid precursor protein (APP)
- The calcium homeostasis modulator 1 (CALHM1) is a recently identified multipass transmembrane glycoprotein that controls cytosolic Ca2+ concentration and Abeta levels
- While some studies suggest CALHM1 is significantly associated with risk of AD, other reports suggest there is no link
- CALHM1 has been suggested to modulate the Ca2+-dependent proteolytic process of APP through controlling the level of cytosolic Ca2+.