PIPA520983

TCTN1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA520983-Each-of-1 In Stock ₹ 46,502.50

PIPA520983 - Each of 1

₹ 46,502.50

In Stock

Quantity

1

Base Price: ₹ 46,502.50

GST (18%): ₹ 8,370.45

Total Price: ₹ 54,872.95

Antigen

TCTN1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TCTN1

Gene Alias

G730031O11Rik; JBTS13; RGD1566266; TCTN1; TECT1; tectonic family member 1; tectonic-1; UNQ9369/PRO34160

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

654470, 79600

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunohistochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q2MV58, Q8BZ64

Gene Symbols

TCTN1

Immunogen

A 15 amino acid peptide near the amino terminus of human TCTN1.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is mouse kidney tissue lysate
  • PA5-20983 can be used with blocking peptide PEP-1097
  • TCTN1 is the founding member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube
  • During embryonic development, TCTN1 is expressed in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node
  • Mice expressing mutant TCTN1 die between E13
  • 5 and E16
  • 5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator
  • At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.