ZEB2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA520980-Each-of-1 | In Stock | ₹ 49,617.50 |
PIPA520980 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 49,617.50
GST (18%): ₹ 8,931.15
Total Price: ₹ 58,548.65
Antigen
ZEB2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Zeb2
Gene Alias
9130203F04Rik; D130016B08Rik; HRIHFB2411; HSPC082; KIAA0569; SIP1; SIP-1; SMAD interacting protein 1; smad-interacting protein 1; SMADIP1; Zeb2; ZFHX1B; Zfx1b; Zfxh1b; zinc finger E-box binding homeobox 2; zinc finger E-box-binding homeobox 2; zinc finger homeobox 1b; zinc finger homeobox protein 1b
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
24136, 311071, 9839
Content And Storage
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 0.02% sodium azide
Gene Accession No.
O60315, Q9R0G7
Gene Symbols
Zeb2
Immunogen
An 18 amino acid peptide near the carboxy terminus of human ZEB2.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Due to post-translational modifications, ZEB2 migrates at ∽180kDa in SDS-PAGE
- A suggested positive control is Jurkat cell lysate
- PA5-20980 can be used with blocking peptide PEP-1094
- ZEB2, initially identified as Smad interacting-protein 1, is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs
- Like the homologous ZEB1, ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition, a genetic program controlling cell migration during embryonic development and wound healing, in vitro
- ZEB2 can also protect cells from DNA damage-induced apoptosis, suggesting that its expression may contribute to tumor progression
- Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues, indicating that its localization may be regulated in normal and tumor tissues
- Mutations in this gene are also associated with Hirschsprung disease/Mowat-Wilson syndrome.