PIPA521121

ZNF281 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA521121-Each-of-1 In Stock ₹ 48,905.50

PIPA521121 - Each of 1

₹ 48,905.50

In Stock

Quantity

1

Base Price: ₹ 48,905.50

GST (18%): ₹ 8,802.99

Total Price: ₹ 57,708.49

Antigen

ZNF281

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ZNF281

Gene Alias

GC-box-binding zinc finger protein 1; GZP1; Transcription factor ZBP-99; ZBP99; ZBP-99; Zfp281; Zinc finger DNA-binding protein 99; zinc finger protein 281; ZNF281; ZNP-99; ZNP-99 transcription factor

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

226442, 23528

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

Q99LI5, Q9Y2X9

Gene Symbols

Zfp281, ZNF281

Immunogen

A 19 amino acid peptide near the carboxy terminus of human ZFP281.

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is A-20 cell lysate
  • PA5-21121 can be used with blocking peptide PEP-1235
  • ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters
  • It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression
  • ZFP281 also interacts with many other other transcription factors, such as Sp1 to repress vimentin gene transcription
  • ZFP281 has also been shown to control embryonic stem cell pluripotency by direct regulating specific target genes
  • ZFP281 phyically interacts with the transcription factos POU5F1, Sox2, and NANOG
  • Gene expression microarray anlysis indicated that some ZFP281 target genes were activated, while others were repressed upon knockdown of ZFP281 expression, showing that ZFP281 plays bifuctinal roles in regulating gene expression in stem cells.